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Population shift of binding pocket size and dynamic correlation analysis shed new light on the anticooperative mechanism of P(II) protein
P(II) protein is one of the largest families of signal transduction proteins in archaea, bacteria, and plants, controlling key processes of nitrogen assimilation. An intriguing characteristic for many P(II) proteins is that the three ligand binding sites exhibit anticooperative allosteric regulation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282546/ https://www.ncbi.nlm.nih.gov/pubmed/24218085 http://dx.doi.org/10.1002/prot.24477 |