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Function of mutant and wild-type plexinB1 in prostate cancer cells

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumors, indicating a role for plexinB1 in the pathogenesis of prostate...

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Detalles Bibliográficos
Autores principales: Damola, Adebiyi, Legendre, Anne, Ball, Stephen, Masters, John R, Williamson, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282548/
https://www.ncbi.nlm.nih.gov/pubmed/23775445
http://dx.doi.org/10.1002/pros.22678