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Presynaptic pH and vesicle fusion in Drosophila larvae neurones

Both intracellular pH (pH(i)) and synaptic cleft pH change during neuronal activity yet little is known about how these pH shifts might affect synaptic transmission by influencing vesicle fusion. To address this we imaged pH- and Ca(2+)-sensitive fluorescent indicators (HPTS, Oregon green) in bouton...

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Detalles Bibliográficos
Autores principales: Caldwell, Lesley, Harries, Peter, Sydlik, Sebastian, Schwiening, Christof J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282566/
https://www.ncbi.nlm.nih.gov/pubmed/23649934
http://dx.doi.org/10.1002/syn.21678