Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion

Sister chromatid cohesion mediated by the cohesin complex is essential for chromosome segregation during cell division. Using functional genomic screening, we identify a set of 26 pre-mRNA splicing factors that are required for sister chromatid cohesion in human cells. Loss of spliceosome subunits i...

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Detalles Bibliográficos
Autores principales: Sundaramoorthy, Sriramkumar, Vázquez-Novelle, María Dolores, Lekomtsev, Sergey, Howell, Michael, Petronczki, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282572/
https://www.ncbi.nlm.nih.gov/pubmed/25257310
http://dx.doi.org/10.15252/embj.201488244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282572/
https://www.ncbi.nlm.nih.gov/pubmed/25257310
http://dx.doi.org/10.15252/embj.201488244

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