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Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion

Sister chromatid cohesion mediated by the cohesin complex is essential for chromosome segregation during cell division. Using functional genomic screening, we identify a set of 26 pre-mRNA splicing factors that are required for sister chromatid cohesion in human cells. Loss of spliceosome subunits i...

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Detalles Bibliográficos
Autores principales:	Sundaramoorthy, Sriramkumar, Vázquez-Novelle, María Dolores, Lekomtsev, Sergey, Howell, Michael, Petronczki, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282572/ https://www.ncbi.nlm.nih.gov/pubmed/25257310 http://dx.doi.org/10.15252/embj.201488244

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