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Using siRNA to define functional interactions between melanopsin and multiple G Protein partners

Melanopsin expressing photosensitive retinal ganglion cells (pRGCs) represent a third class of ocular photoreceptors and mediate a range of non-image forming responses to light. Melanopsin is a G protein coupled receptor (GPCR) and existing data suggest that it employs a membrane bound signalling ca...

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Detalles Bibliográficos
Autores principales: Hughes, Steven, Jagannath, Aarti, Hickey, Doron, Gatti, Silvia, Wood, Matthew, Peirson, Stuart N., Foster, Russell G., Hankins, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282707/
https://www.ncbi.nlm.nih.gov/pubmed/24958088
http://dx.doi.org/10.1007/s00018-014-1664-6