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Long-Term Outcomes and Dynamics of Mutants Associated with Lamivudine-Adefovir Rescue Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B

BACKGROUND/AIMS: To investigate the association between the baseline profiles and dynamics of hepatitis B virus (HBV) DNA polymerase gene mutations and the long-term virological response of lamivudine (LAM)-adefovir (ADV) combination therapy in patients with LAM-resistant chronic hepatitis B. METHOD...

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Detalles Bibliográficos
Autores principales: Kim, Jihyun, Lee, Sae Hwan, Kim, Hong Soo, Choi, Kanghyug, Jeong, Soung Won, Kim, Sang Gyune, Jang, Jae Young, Kim, Young Seok, Kim, Boo Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282849/
https://www.ncbi.nlm.nih.gov/pubmed/25287170
http://dx.doi.org/10.5009/gnl14018