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A Phase I Study of High-Dose Calcitriol in Combination with Temozolomide for Patients with Metastatic Melanoma
Background: Temozolomide is efficacious as an oral alternative for patients with metastatic melanoma (MM). Calcitriol has anti-proliferative properties and vitamin D receptor (VDR) polymorphisms are associated with alterations in melanoma susceptibility and progression. Methods: Tem 150 mg/m(2) was...
Autores principales: | Pettijohn, Erin, Martone, Brenda, Rademaker, Alfred, Kuzel, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282882/ https://www.ncbi.nlm.nih.gov/pubmed/25563456 http://dx.doi.org/10.3390/jpm4040448 |
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