Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG do...

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Detalles Bibliográficos
Autores principales: Schmidt, Hermann Broder, Görlich, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283134/
https://www.ncbi.nlm.nih.gov/pubmed/25562883
http://dx.doi.org/10.7554/eLife.04251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283134/
https://www.ncbi.nlm.nih.gov/pubmed/25562883
http://dx.doi.org/10.7554/eLife.04251

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