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Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG do...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283134/ https://www.ncbi.nlm.nih.gov/pubmed/25562883 http://dx.doi.org/10.7554/eLife.04251 |