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Identification of an env-defective HIV-1 mutant capable of spontaneous reversion to a wild-type phenotype in certain T-cell lines

BACKGROUND: Attempts to eradicate HIV from cellular reservoirs are vital but depend on a clear understanding of how viral variants are transmitted and survive in the different cell types that constitute such reservoirs. Mutations in the env gene of HIV may be able to exert a differential influence o...

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Detalles Bibliográficos
Autores principales: Quan, Yudong, Xu, Hongtao, Kramer, Victor G, Han, Yingshan, Sloan, Richard D, Wainberg, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283149/
https://www.ncbi.nlm.nih.gov/pubmed/25287969
http://dx.doi.org/10.1186/1743-422X-11-177