Increased gene copy number of the vesicle SNARE VAMP7 disrupts human male urogenital development through altered estrogen action

Vesicle transport is intimately connected with key nuclear functions and transcriptional regulation. Here, children born with congenital genitourinary tract masculinization disorders were analyzed by array-Comparative Genomic Hybridization, which revealed the presence of de novo copy number gains on...

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Detalles Bibliográficos
Autores principales: Tannour-Louet, Mounia, Han, Shuo, Louet, Jean-Francois, Zhang, Bin, Romero, Karina, Addai, Josephine, Sahin, Aysegul, Cheung, Sau Wai, Lamb, Dolores J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283218/
https://www.ncbi.nlm.nih.gov/pubmed/24880616
http://dx.doi.org/10.1038/nm.3580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283218/
https://www.ncbi.nlm.nih.gov/pubmed/24880616
http://dx.doi.org/10.1038/nm.3580

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