A dystrophic muscle broadens the contribution and activation of immune cells reacting to rAAV gene transfer

Recombinant adeno-associated viral vectors (rAAVs) are used for therapeutic gene transfer in skeletal muscle, but it is unclear if immune reactivity to gene transfer and persistence of transgene are affected by pathologic conditions such as muscular dystrophy. Thus, we compared dystrophic mice devoi...

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Detalles Bibliográficos
Autores principales: Ferrand, M, Galy, A, Boisgerault, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283385/
https://www.ncbi.nlm.nih.gov/pubmed/25030611
http://dx.doi.org/10.1038/gt.2014.61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283385/
https://www.ncbi.nlm.nih.gov/pubmed/25030611
http://dx.doi.org/10.1038/gt.2014.61

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