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A dystrophic muscle broadens the contribution and activation of immune cells reacting to rAAV gene transfer
Recombinant adeno-associated viral vectors (rAAVs) are used for therapeutic gene transfer in skeletal muscle, but it is unclear if immune reactivity to gene transfer and persistence of transgene are affected by pathologic conditions such as muscular dystrophy. Thus, we compared dystrophic mice devoi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283385/ https://www.ncbi.nlm.nih.gov/pubmed/25030611 http://dx.doi.org/10.1038/gt.2014.61 |