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Deletion of TNF-Like Weak Inducer of Apoptosis (TWEAK) Protects Mice From Adipose and Systemic Impacts of Severe Obesity

OBJECTIVE: To investigate the role of TNF-like weak inducer of apoptosis (TWEAK) in pathological adipose tissue (AT) remodeling and complications of obesity. DESIGN AND METHODS: Wild type (WT) and TWEAK knockout (KO) mice were fed normal diet (ND) or a high fat diet (HFD) for up to 17 weeks. Adipocy...

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Detalles Bibliográficos
Autores principales: Bennett, Grace, Strissel, Katherine J., DeFuria, Jason, Wang, Junpeng, Wu, Dayong, Burkly, Linda C., Obin, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283503/
https://www.ncbi.nlm.nih.gov/pubmed/24616441
http://dx.doi.org/10.1002/oby.20726