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Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain

OBJECTIVES: Blockade of transient receptor potential vanilloid 1 (TRPV1) with systemic antagonists attenuates osteoarthritis (OA) pain behaviour in rat models, but on-target-mediated hyperthermia has halted clinical trials. The present study investigated the potential for targeting TRPV1 receptors w...

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Detalles Bibliográficos
Autores principales:	Kelly, S, Chapman, R J, Woodhams, S, Sagar, D R, Turner, J, Burston, J J, Bullock, C, Paton, K, Huang, J, Wong, A, McWilliams, D F, Okine, B N, Barrett, D A, Hathway, G J, Walsh, D A, Chapman, V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2015
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283626/ https://www.ncbi.nlm.nih.gov/pubmed/24152419 http://dx.doi.org/10.1136/annrheumdis-2013-203413

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