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Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications

As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...

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Detalles Bibliográficos
Autores principales: Rath, Timo, Baker, Kristi, Pyzik, Michal, Blumberg, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283642/
https://www.ncbi.nlm.nih.gov/pubmed/25601863
http://dx.doi.org/10.3389/fimmu.2014.00664