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Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications
As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...
Autores principales: | Rath, Timo, Baker, Kristi, Pyzik, Michal, Blumberg, Richard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283642/ https://www.ncbi.nlm.nih.gov/pubmed/25601863 http://dx.doi.org/10.3389/fimmu.2014.00664 |
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