A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

XPD functions in transcription, DNA repair and in cell cycle control. Mutations in human XPD (also known as ERCC2) mainly cause three clinical phenotypes: xeroderma pigmentosum (XP), Cockayne syndrome (XP/CS) and trichothiodystrophy (TTD), and only XP patients have a high predisposition to developin...

Descripción completa

Detalles Bibliográficos
Autores principales: Stettler, Karin, Li, Xiaoming, Sandrock, Björn, Braga-Lagache, Sophie, Heller, Manfred, Dümbgen, Lutz, Suter, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283652/
https://www.ncbi.nlm.nih.gov/pubmed/25431422
http://dx.doi.org/10.1242/dmm.016907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283652/
https://www.ncbi.nlm.nih.gov/pubmed/25431422
http://dx.doi.org/10.1242/dmm.016907

Ejemplares similares