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A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

BACKGROUND: There is currently great interest in the incorporation of genetic susceptibility loci into screening models to identify individuals at high risk of disease. Here, we present the first risk prediction model including all 46 known genetic loci associated with rheumatoid arthritis (RA). MET...

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Detalles Bibliográficos
Autores principales: Yarwood, Annie, Han, Buhm, Raychaudhuri, Soumya, Bowes, John, Lunt, Mark, Pappas, Dimitrios A, Kremer, Joel, Greenberg, Jeffrey D, Plenge, Robert, Worthington, Jane, Barton, Anne, Eyre, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283663/
https://www.ncbi.nlm.nih.gov/pubmed/24092415
http://dx.doi.org/10.1136/annrheumdis-2013-204133