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A review of piscine islet xenotransplantation using wild-type tilapia donors and the production of transgenic tilapia expressing a “humanized” tilapia insulin

Most islet xenotransplantation laboratories have focused on porcine islets, which are both costly and difficult to isolate. Teleost (bony) fish, such as tilapia, possess macroscopically visible distinct islet organs called Brockmann bodies which can be inexpensively harvested. When transplanted into...

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Detalles Bibliográficos
Autores principales: Wright, James R, Yang, Hua, Hyrtsenko, Olga, Xu, Bao-You, Yu, Weiming, Pohajdak, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283710/
https://www.ncbi.nlm.nih.gov/pubmed/25040337
http://dx.doi.org/10.1111/xen.12115