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NF-κB Essential Modulator Deficiency Leading to Disseminated Cutaneous Atypical Mycobacteria

NF-κB essential modulator (NEMO) is a kinase integral to the macrophage TNF-α pathway, which leads to the intracellular destruction of Mycobacteria species. Defects in the NEMO pathway result in spectrum of diseases, including but not limited to ectodermal dysplasia, Mendelian susceptibility to myco...

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Detalles Bibliográficos
Autores principales: Braue, Jonathan, Murugesan, Vagishwari, Holland, Steven, Patel, Nishit, Naik, Eknath, Leiding, Jennifer, Yacoub, Abraham Tareq, Prieto-Granada, Carlos N, Greene, John Norman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283928/
https://www.ncbi.nlm.nih.gov/pubmed/25574369
http://dx.doi.org/10.4084/MJHID.2015.010