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NF-κB Essential Modulator Deficiency Leading to Disseminated Cutaneous Atypical Mycobacteria
NF-κB essential modulator (NEMO) is a kinase integral to the macrophage TNF-α pathway, which leads to the intracellular destruction of Mycobacteria species. Defects in the NEMO pathway result in spectrum of diseases, including but not limited to ectodermal dysplasia, Mendelian susceptibility to myco...
Autores principales: | Braue, Jonathan, Murugesan, Vagishwari, Holland, Steven, Patel, Nishit, Naik, Eknath, Leiding, Jennifer, Yacoub, Abraham Tareq, Prieto-Granada, Carlos N, Greene, John Norman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Università Cattolica del Sacro Cuore
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283928/ https://www.ncbi.nlm.nih.gov/pubmed/25574369 http://dx.doi.org/10.4084/MJHID.2015.010 |
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