Kinetic Mechanisms Governing Stable Ribonucleotide Incorporation in Individual DNA Polymerase Complexes

[Image: see text] Ribonucleoside triphosphates (rNTPs) are frequently incorporated during DNA synthesis by replicative DNA polymerases (DNAPs), and once incorporated are not efficiently edited by the DNAP exonucleolytic function. We examined the kinetic mechanisms that govern selection of complement...

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Detalles Bibliográficos
Autores principales: Dahl, Joseph M., Wang, Hongyun, Lázaro, José M., Salas, Margarita, Lieberman, Kate R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283934/
https://www.ncbi.nlm.nih.gov/pubmed/25478721
http://dx.doi.org/10.1021/bi501216a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283934/
https://www.ncbi.nlm.nih.gov/pubmed/25478721
http://dx.doi.org/10.1021/bi501216a

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