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Assessment of fully automated antibody homology modeling protocols in molecular operating environment

The success of antibody-based drugs has led to an increased demand for predictive computational tools to assist antibody engineering efforts surrounding the six hypervariable loop regions making up the antigen binding site. Accurate computational modeling of isolated protein loop regions can be quit...

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Detalles Bibliográficos
Autores principales: Maier, Johannes K X, Labute, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284016/
https://www.ncbi.nlm.nih.gov/pubmed/24715627
http://dx.doi.org/10.1002/prot.24576