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Assessment of fully automated antibody homology modeling protocols in molecular operating environment
The success of antibody-based drugs has led to an increased demand for predictive computational tools to assist antibody engineering efforts surrounding the six hypervariable loop regions making up the antigen binding site. Accurate computational modeling of isolated protein loop regions can be quit...
Autores principales: | Maier, Johannes K X, Labute, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284016/ https://www.ncbi.nlm.nih.gov/pubmed/24715627 http://dx.doi.org/10.1002/prot.24576 |
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