Control of Protein Particle Formation During Ultrafiltration/Diafiltration Through Interfacial Protection

This study investigates the mechanism of protein particle formation during ultrafiltration/diafiltration (UF/DF), finding that agitation drives particle formation by promoting protein-interface adsorption and desorption. Low conductivity and the presence of surfactant reduced the level of particle f...

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Detalles Bibliográficos
Autores principales: Callahan, Daniel J, Stanley, Bradford, Li, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Pharmaceutical Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284022/
https://www.ncbi.nlm.nih.gov/pubmed/24449131
http://dx.doi.org/10.1002/jps.23861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284022/
https://www.ncbi.nlm.nih.gov/pubmed/24449131
http://dx.doi.org/10.1002/jps.23861

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