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Control of Protein Particle Formation During Ultrafiltration/Diafiltration Through Interfacial Protection

This study investigates the mechanism of protein particle formation during ultrafiltration/diafiltration (UF/DF), finding that agitation drives particle formation by promoting protein-interface adsorption and desorption. Low conductivity and the presence of surfactant reduced the level of particle f...

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Detalles Bibliográficos
Autores principales:	Callahan, Daniel J, Stanley, Bradford, Li, Yuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Pharmaceutical Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284022/ https://www.ncbi.nlm.nih.gov/pubmed/24449131 http://dx.doi.org/10.1002/jps.23861

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