Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells

There is an increasing prevalence of Alzheimer’s disease (AD), which has become a public health issue. However, the underlying mechanisms for the pathogenesis of AD are not fully understood, and the current therapeutic drugs cannot produce acceptable efficacy in AD patients. Previous animal studies...

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Detalles Bibliográficos
Autores principales: Zhang, Li-Fang, Zhou, Zhi-Wei, Wang, Zhen-Hai, Du, Yan-Hui, He, Zhi-Xu, Cao, Chuanhai, Zhou, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284031/
https://www.ncbi.nlm.nih.gov/pubmed/25565776
http://dx.doi.org/10.2147/DDDT.S71106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284031/
https://www.ncbi.nlm.nih.gov/pubmed/25565776
http://dx.doi.org/10.2147/DDDT.S71106

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