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Sirtuin 1 activator SRT2104 protects Huntington's disease mice

Sirtuin 1 is a nicotinamide adenine dinucleotide-dependent protein deacetylase which regulates longevity and improves metabolism. Activation of Sirtuin 1 confers beneficial effects in models of neurodegenerative diseases. We and others have provided convincing evidence that overexpression of Sirtuin...

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Detalles Bibliográficos
Autores principales: Jiang, Mali, Zheng, Jennifer, Peng, Qi, Hou, Zhipeng, Zhang, Jiangyang, Mori, Susumu, Ellis, James L, Vlasuk, George P, Fries, Harvey, Suri, Vipin, Duan, Wenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284130/
https://www.ncbi.nlm.nih.gov/pubmed/25574479
http://dx.doi.org/10.1002/acn3.135