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IL-15 complexes induce NK cell and T cell responses independent of type I IFN signalling during rhinovirus infection

Rhinoviruses are the most common virus to infect man causing a range of serious respiratory diseases including exacerbations of asthma and COPD. Type I IFN and IL-15 are thought to be required for antiviral immunity however their function during rhinovirus infection in vivo is undefined. In RV infec...

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Detalles Bibliográficos
Autores principales: Jayaraman, Annabelle, Jackson, David J., Message, Simon D., Pearson, Rebecca M., Aniscenko, Julia, Caramori, Gaetano, Mallia, Patrick, Papi, Alberto, Shamji, Betty, Edwards, Matt, Westwick, John, Hansel, Trevor, Stanciu, Luminita A., Johnston, Sebastian L., Bartlett, Nathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284198/
https://www.ncbi.nlm.nih.gov/pubmed/24472849
http://dx.doi.org/10.1038/mi.2014.2