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Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

Nuclear organization has been implicated in regulating gene activity. Recently, large developmentally regulated regions of the genome dynamically associated with the nuclear lamina have been identified. However, little is known about how these lamina-associated domains (LADs) are directed to the nuc...

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Detalles Bibliográficos
Autores principales: Harr, Jennifer C., Luperchio, Teresa Romeo, Wong, Xianrong, Cohen, Erez, Wheelan, Sarah J., Reddy, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284222/
https://www.ncbi.nlm.nih.gov/pubmed/25559185
http://dx.doi.org/10.1083/jcb.201405110