Cargando…

Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability

Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid–specific transcription but has distinct roles in oocyte meiotic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Pattabiraman, Shrivatsav, Baumann, Claudia, Guisado, Daniela, Eppig, John J., Schimenti, John C., De La Fuente, Rabindranath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284233/
https://www.ncbi.nlm.nih.gov/pubmed/25547156
http://dx.doi.org/10.1083/jcb.201404109