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Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability
Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid–specific transcription but has distinct roles in oocyte meiotic p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284233/ https://www.ncbi.nlm.nih.gov/pubmed/25547156 http://dx.doi.org/10.1083/jcb.201404109 |