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Neuroprotective effect of masitinib in rats with postischemic stroke

This study evaluated the therapeutic potential of masitinib, an oral tyrosine kinase inhibitor with activity against c-Kit and platelet-derived growth factor receptors (PDGFR), to reduce ischemic brain area and neurological deficit. Using a well-established filament model of ischemic stroke in rats,...

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Detalles Bibliográficos
Autores principales: Kocic, Ivan, Kowianski, Przemyslaw, Rusiecka, Izabela, Lietzau, Grazyna, Mansfield, Colin, Moussy, Alain, Hermine, Olivier, Dubreuil, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284372/
https://www.ncbi.nlm.nih.gov/pubmed/25344204
http://dx.doi.org/10.1007/s00210-014-1061-6