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Neuroprotective effect of masitinib in rats with postischemic stroke
This study evaluated the therapeutic potential of masitinib, an oral tyrosine kinase inhibitor with activity against c-Kit and platelet-derived growth factor receptors (PDGFR), to reduce ischemic brain area and neurological deficit. Using a well-established filament model of ischemic stroke in rats,...
Autores principales: | Kocic, Ivan, Kowianski, Przemyslaw, Rusiecka, Izabela, Lietzau, Grazyna, Mansfield, Colin, Moussy, Alain, Hermine, Olivier, Dubreuil, Patrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284372/ https://www.ncbi.nlm.nih.gov/pubmed/25344204 http://dx.doi.org/10.1007/s00210-014-1061-6 |
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