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PIP(2)-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6

Among critical aspects of voltage-gated potassium (Kv) channels' functioning is the effective communication between their two composing domains, the voltage sensor (VSD) and the pore. This communication, called coupling, might be transmitted directly through interactions between these domains a...

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Detalles Bibliográficos
Autores principales: Kasimova, Marina A., Zaydman, Mark A., Cui, Jianmin, Tarek, Mounir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284513/
https://www.ncbi.nlm.nih.gov/pubmed/25559286
http://dx.doi.org/10.1038/srep07474