Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG

The hypoxic tumor microenvironment generates oxidative Endoplasmic Reticulum (ER) stress, resulting in protein misfolding and unfolded protein response (UPR). UPR induces several molecular chaperones including heat-shock protein 90 (HSP90), which corrects protein misfolding and improves survival of...

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Detalles Bibliográficos
Autores principales: Saha, Subhrajit, Bhanja, Payel, Partanen, Ari, Zhang, Wei, Liu, Laibin, Tomé, Wolfgang, Guha, Chandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284617/
https://www.ncbi.nlm.nih.gov/pubmed/25594042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284617/
https://www.ncbi.nlm.nih.gov/pubmed/25594042

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