AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer

Depletion of cellular energy activates the AMP-activated kinase (AMPK) to favor energy-producing catabolic processes during tumorigenesis. Using a panel of in vitro cell lines and resected tumors, we investigated the therapeutic value of manipulating AMPK in prostate cancer (PC). Phospho-AMPK expres...

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Detalles Bibliográficos
Autores principales: Choudhury, Yashmin, Yang, Zichu, Ahmad, Imran, Nixon, Colin, Salt, Ian P., Leung, Hing Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284621/
https://www.ncbi.nlm.nih.gov/pubmed/25594043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284621/
https://www.ncbi.nlm.nih.gov/pubmed/25594043

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