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An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

DNA methylation has a great potential for understanding the aetiology of common complex traits such as Type 2 diabetes (T2D). Here we perform genome-wide methylated DNA immunoprecipitation sequencing (MeDIP-seq) in whole-blood-derived DNA from 27 monozygotic twin pairs and follow up results with rep...

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Detalles Bibliográficos
Autores principales: Yuan, Wei, Xia, Yudong, Bell, Christopher G., Yet, Idil, Ferreira, Teresa, Ward, Kirsten J., Gao, Fei, Loomis, A. Katrina, Hyde, Craig L., Wu, Honglong, Lu, Hanlin, Liu, Yuan, Small, Kerrin S., Viñuela, Ana, Morris, Andrew P., Berdasco, María, Esteller, Manel, Brosnan, M. Julia, Deloukas, Panos, McCarthy, Mark I., John, Sally L., Bell, Jordana T., Wang, Jun, Spector, Tim D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284644/
https://www.ncbi.nlm.nih.gov/pubmed/25502755
http://dx.doi.org/10.1038/ncomms6719