DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a singl...

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Detalles Bibliográficos
Autores principales: Nguyen, Long V., Cox, Claire L., Eirew, Peter, Knapp, David J. H. F., Pellacani, Davide, Kannan, Nagarajan, Carles, Annaick, Moksa, Michelle, Balani, Sneha, Shah, Sohrab, Hirst, Martin, Aparicio, Samuel, Eaves, Connie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284657/
https://www.ncbi.nlm.nih.gov/pubmed/25532760
http://dx.doi.org/10.1038/ncomms6871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284657/
https://www.ncbi.nlm.nih.gov/pubmed/25532760
http://dx.doi.org/10.1038/ncomms6871

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