Cargando…

DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a singl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Long V., Cox, Claire L., Eirew, Peter, Knapp, David J. H. F., Pellacani, Davide, Kannan, Nagarajan, Carles, Annaick, Moksa, Michelle, Balani, Sneha, Shah, Sohrab, Hirst, Martin, Aparicio, Samuel, Eaves, Connie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284657/ https://www.ncbi.nlm.nih.gov/pubmed/25532760 http://dx.doi.org/10.1038/ncomms6871

Ejemplares similares

Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells
por: Makarem, Maisam, et al.
Publicado: (2013)

Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation
por: Lefort, Sylvain, et al.
Publicado: (2019)

Human Milk Protein Production in Xenografts of Genetically Engineered Bovine Mammary Epithelial Stem Cells
por: Martignani, Eugenio, et al.
Publicado: (2010)

DNA barcoded competitive clone-initiating cell analysis reveals novel features of metastatic growth in a cancer xenograft model
por: Aalam, Syed Mohammed Musheer, et al.
Publicado: (2022)

Single-cell analysis of autophagy activity in normal and de novo transformed human mammary cells
por: Lefort, Sylvain, et al.
Publicado: (2020)

Modeling the process of human tumorigenesis
por: Balani, Sneha, et al.
Publicado: (2017)

Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression
por: Sloma, Ivan, et al.
Publicado: (2020)

RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia
por: Islam, Rashedul, et al.
Publicado: (2023)

High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations
por: Hui, Tony, et al.
Publicado: (2018)

Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones
por: Ludden, Catherine, et al.
Publicado: (2020)

Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity
por: Poglio, Sandrine, et al.
Publicado: (2020)

THE EXPERIMENTAL PRODUCTION OF COMBINATION FORMS OF VIRUS : II. A STUDY OF SERIAL PASSAGE IN THE ALLANTOIC SAC OF AGENTS THAT COMBINE THE ANTIGENS OF TWO DISTINCT INFLUENZA A STRAINS
por: Hirst, George K., et al.
Publicado: (1953)

1457. Serial Passage of Enterobacteriaceae to Explore Development of Carbapenem Resistance
por: Nissim, Yosef, et al.
Publicado: (2020)

Evolution of SIVmac239 following serial passaging in humanized mice
por: Curlin, James Z., et al.
Publicado: (2022)

Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer
por: Pellacani, Davide, et al.
Publicado: (2019)

Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice
por: Koskiniemi, Sanna, et al.
Publicado: (2013)

Enhanced Virulence of Aeromonas hydrophila Is Induced by Stress and Serial Passaging in Mice
por: Kim, Kyoo-Tae, et al.
Publicado: (2021)

Serial passaging affects stromal cell mechanosensitivity on hyaluronic acid hydrogels
por: Sumey, Jenna L., et al.
Publicado: (2023)

Serial cytogenetic studies of human colonic tumour xenografts.
por: Reeves, B. R., et al.
Publicado: (1978)

Characterization of defective-interfering RNAs of rubella virusgenerated during serial undiluted passage
por: Derdeyn, Cynthia A., et al.
Publicado: (1995)

Preparation and characterization of an attenuated porcine epidemic diarrhea virus strain by serial passaging
por: Jie, Tao, et al.
Publicado: (2018)

Biological Characterization and Evolution of Bacteriophage T7-△holin During the Serial Passage Process
por: Xu, Hai, et al.
Publicado: (2021)

The mutational dynamics of the SARS-CoV-2 virus in serial passages in vitro
por: Sonnleitner, Sissy Therese, et al.
Publicado: (2022)

Evolution of cefiderocol resistance in Stenotrophomonas maltophilia using in vitro serial passage techniques
por: Werth, Brian J., et al.
Publicado: (2022)

An in vivo orthotopic serial passaging model for a metastatic renal cancer study
por: Nishida, Jun, et al.
Publicado: (2022)

Subclonal heterogeneity and evolution in breast cancer
por: Mavrommati, Ioanna, et al.
Publicado: (2021)

Accurate Identification of Subclones in Tumor Genomes
por: Ahmadinejad, Navid, et al.
Publicado: (2022)

A Virulent PEDV Strain FJzz1 with Genomic Mutations and Deletions at the High Passage Level Was Attenuated in Piglets via Serial Passage In Vitro
por: Chen, Pengfei, et al.
Publicado: (2021)

Effects of serial passage on the endocrine response and steroid metabolism of a rat mammary carcinoma.
por: Miller, W. R.
Publicado: (1980)

Growth characteristics of human colorectal tumours during serial passage in immune-deprived mice.
por: Houghton, J. A., et al.
Publicado: (1978)

Complete Genome Sequence of an Attenuated Duck Enteritis Virus Obtained by In Vitro Serial Passage
por: Yang, Chenghuai, et al.
Publicado: (2013)

Serial passage of HIV-2F: a pigtail macaque model for HIV emergence
por: Bond, Nell G, et al.
Publicado: (2014)

Attractive and repulsive serial dependence: The role of task relevance, the passage of time, and the number of stimuli
por: Ceylan, Gizay, et al.
Publicado: (2023)

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
por: Woo, Xing Yi, et al.
Publicado: (2021)

Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts
por: Imai, Toshio, et al.
Publicado: (2023)

Phenotypic stability and metastatic behaviour of serially xenografted rat mesotheliomas.
por: Edwards, R. E., et al.
Publicado: (1990)

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells
por: Kawamura, Eiko, et al.
Publicado: (2013)

Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV16 E6/E7-Induced Perturbation
por: Kang, Sung Yoon Catherine, et al.
Publicado: (2015)

Integrative Multi-OMICs Identifies Therapeutic Response Biomarkers and Confirms Fidelity of Clinically Annotated, Serially Passaged Patient-Derived Xenografts Established from Primary and Metastatic Pediatric and AYA Solid Tumors
por: Pandya, Pankita H., et al.
Publicado: (2022)

A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
por: Burleigh, Angela, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_c8bug028qo45geg1gl9udum00c