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The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell–cell adhesion

Dividing epithelial cells need to coordinate spindle positioning with shape changes to maintain cell–cell adhesion. Microtubule interactions with the cell cortex regulate mitotic spindle positioning within the plane of division. How the spindle crosstalks with the actin cytoskeleton to ensure faithf...

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Detalles Bibliográficos
Autores principales: Vitiello, Elisa, Ferreira, Jorge G., Maiato, Helder, Balda, Maria S., Matter, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284802/
https://www.ncbi.nlm.nih.gov/pubmed/25518808
http://dx.doi.org/10.1038/ncomms6826