Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia

Cilia dysfunction underlies a class of human diseases with variable penetrance in different organ systems. Across eukaryotes, intraflagellar transport (IFT) facilitates cilia biogenesis and cargo trafficking, but our understanding of mammalian IFT is insufficient. Here we perform live analysis of ci...

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Detalles Bibliográficos
Autores principales: Williams, Corey L., McIntyre, Jeremy C., Norris, Stephen R., Jenkins, Paul M., Zhang, Lian, Pei, Qinglin, Verhey, Kristen, Martens, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284812/
https://www.ncbi.nlm.nih.gov/pubmed/25504142
http://dx.doi.org/10.1038/ncomms6813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284812/
https://www.ncbi.nlm.nih.gov/pubmed/25504142
http://dx.doi.org/10.1038/ncomms6813

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