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Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors
G protein-coupled receptors (GPCRs) modulate most physiological functions but are also critically involved in numerous pathological states. Approximately a third of marketed drugs target GPCRs, which places this family of receptors in the main arena of pharmacological pre-clinical and clinical resea...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284998/ https://www.ncbi.nlm.nih.gov/pubmed/25610398 http://dx.doi.org/10.3389/fphar.2014.00289 |