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Partial Hepatectomy in Acetylation-Deficient BubR1 Mice Corroborates that Chromosome Missegregation Initiates Tumorigenesis

BACKGROUND: Aneuploidy has been suggested as one of the major causes of cancer from the time of Boveri. In support of this notion, many studies have shown that cancer cells exhibit aneuploidy. However, there are evidences that do not support the aneuploidy hypothesis. We have previously reported tha...

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Detalles Bibliográficos
Autores principales: Lee, Yoo-Kyung, Park, Inai, Lee, Hyunsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285024/
https://www.ncbi.nlm.nih.gov/pubmed/25559578
http://dx.doi.org/10.3803/EnM.2014.29.4.561