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Challenges of Clinical Trial Design for Targeted Agents Against Pediatric Leukemias
The past 40 years have seen significant improvements in both event-free and overall survival for children with acute lymphoblastic and acute myeloid leukemia (ALL and AML, respectively). Serial national and international clinical trials have optimized the use of conventional chemotherapeutic drugs a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285052/ https://www.ncbi.nlm.nih.gov/pubmed/25610810 http://dx.doi.org/10.3389/fonc.2014.00374 |