Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis

An FAD-dependent monooxygenase encoding gene (SorbC) was cloned from Penicillium chrysogenum E01-10/3 and expressed as a soluble protein in Escherichia coli. The enzyme efficiently performed the oxidative dearomatisation of sorbicillin and dihydrosorbicillin to give sorbicillinol and dihydrosorbicil...

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Detalles Bibliográficos
Autores principales: Fahad, Ahmed al, Abood, Amira, Fisch, Katja M., Osipow, Anna, Davison, Jack, Avramović, Marija, Butts, Craig P., Piel, Jörn, Simpson, Thomas J., Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285102/
https://www.ncbi.nlm.nih.gov/pubmed/25580210
http://dx.doi.org/10.1039/c3sc52911h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285102/
https://www.ncbi.nlm.nih.gov/pubmed/25580210
http://dx.doi.org/10.1039/c3sc52911h

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