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Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α
Alterations in the expression and activity of the transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α (ppargc1a or PGC-1α) have been reported in multiple movement disorders, yet it is unclear how a lack of PGC-1α impacts transcription and function of the cerebellu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285109/ https://www.ncbi.nlm.nih.gov/pubmed/25610371 http://dx.doi.org/10.3389/fncel.2014.00441 |