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Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition
Acivicin is a natural product with diverse biological activities. Several decades ago its clinical application in cancer treatment was explored but failed due to unacceptable toxicity. The causes behind the desired and undesired biological effects have never been elucidated and only limited informat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285139/ https://www.ncbi.nlm.nih.gov/pubmed/25580214 http://dx.doi.org/10.1039/c4sc02339k |